human SOX13 Over-expression AAV

Name 
AAV-h-SOX13
Cat No 
AAV-224014
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SOX13.

AAV-224014
AAV-h-SOX13

Ready-to-use AAV expressing Human SOX13 (SRY-box 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ICA12; islet cell antibody 12; islet cell antigen 12; Sox-13; SRY (sex determining region Y)-box 13; SRY-related HMG-box gene 13; transcription factor SOX-13; type 1 diabetes autoantigen ICA12
Description (eCommerce)
SOX13 [SRY (sex determining region Y)-box 13] is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12 [taken from NCBI Entrez Gene (Gene ID: 9580].
Description (Vector)
SOX13 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.
Gene ID
9580
Gene Name (eCommerce)
SRY-box 13
Gene Name (Vector)
SRY-box 13
Gene Symbol
SOX13
HGNC ID
HGNC:11192
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
Protein Name (eCommerce)
Transcription factor SOX-13
RefSeq ID
NM_005686
RefSeq Synonyms
NM_005686, BC106038,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
SOX13 [SRY (sex determining region Y)-box 13] is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12 [taken from NCBI Entrez Gene (Gene ID: 9580].
UniGene ID
Hs.201671
UniProt ID (eCommerce)
Q9UN79

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.