human SOD3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223983
Availability:
3-5 weeks
Name:
AAV-h-SOD3
This is an AAV expressing Human SOD3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SOD3
- Gene Name
- superoxide dismutase 3, extracellular
- Gene ID
- 6649
- Gene Synonyms
- EC-SOD
- ORF Size
- 723 bp
- RefSeq#
- BC014418
- Gene Description
- SOD3 encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
- UniGene ID
- Hs.2420
- HGNC ID
- HGNC:11181
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