human SOCS6 Over-expression AAV

Name 
AAV-h-SOCS6
Cat No 
AAV-223978
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SOCS6.

AAV-223978
AAV-h-SOCS6

Ready-to-use AAV expressing Human SOCS6 (suppressor of cytokine signaling 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIS-4; CIS4; HSPC060; SOCS-4; SOCS-6; SOCS4; SSI4; STAI4; STATI4
Description (Vector)
SOCS6 contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Gene ID
9306
Gene Name (Vector)
suppressor of cytokine signaling 6
Gene Symbol
SOCS6
HGNC ID
HGNC:16833
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_004232
RefSeq Synonyms
NM_004232, BC020082,
Species
human
UniGene ID
Hs.44439

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.