human SNIP1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223832
Availability:
3-5 weeks
Name:
AAV-h-SNIP1
This is an AAV expressing Human SNIP1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SNIP1
- Gene Name
- Smad nuclear interacting protein 1
- Gene ID
- 79753
- Gene Synonyms
- PMRED
- ORF Size
- 1191 bp
- RefSeq#
- BC027040
- Gene Description
- SNIP1 encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
- UniGene ID
- Hs.471951
- HGNC ID
- HGNC:30587
Related Products
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