human SNIP1 Over-expression AAV

Name
AAV-h-SNIP1

Cat No
AAV-223832

Availability
4-5 weeks

This is an AAV expressing Human SNIP1.

AAV-223832

AAV-h-SNIP1

Ready-to-use AAV expressing Human SNIP1 (Smad nuclear interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PMRED

Description (Vector)

SNIP1 encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).

Gene ID

79753

Gene Name (Vector)

Smad nuclear interacting protein 1

Gene Symbol

SNIP1

HGNC ID

HGNC:30587

ORF Size (aa)

1191

ORF Size (bp)

1191 bp

RefSeq ID

NM_024700

RefSeq Synonyms

NM_024700, BC027040,

Species

human

UniGene ID

Hs.471951

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.