human SNCAIP Over-expression AAV

Name
AAV-h-SNCAIP

Cat No
AAV-223825

Availability
4-5 weeks

This is an AAV expressing Human SNCAIP.

AAV-223825

AAV-h-SNCAIP

Ready-to-use AAV expressing Human SNCAIP (synuclein alpha interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Sph1; SYPH1

Description (Vector)

SNCAIP encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.

Gene ID

9627

Gene Name (Vector)

synuclein alpha interacting protein

Gene Symbol

SNCAIP

HGNC ID

HGNC:11139

ORF Size (aa)

1812

ORF Size (bp)

1812 bp

RefSeq ID

NM_005460

RefSeq Synonyms

NM_005460, NM_001308109, NM_001308108, NM_001308107, NM_001308106, NM_001308105, NM_001308100, NM_001242935, BC094759, BC040552, BC033743,

Species

human

UniGene ID

Hs.426463

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.