human SLC12A5 Over-expression AAV

Name 
AAV-h-SLC12A5
Cat No 
AAV-223089
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLC12A5.

AAV-223089
AAV-h-SLC12A5

Ready-to-use AAV expressing Human SLC12A5 (solute carrier family 12 member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EIEE34; EIG14; hKCC2; KCC2
Description (Vector)
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.
Gene ID
57468
Gene Name (Vector)
solute carrier family 12 member 5
Gene Symbol
SLC12A5
HGNC ID
HGNC:13818
ORF Size (aa)
3351
ORF Size (bp)
3351 bp
RefSeq ID
NM_020708
RefSeq Synonyms
NM_020708, NM_001134771, BC132670, BC132668,
Species
human
UniGene ID
Hs.21413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.