human SGTB Over-expression AAV

Name 
AAV-h-SGTB
Cat No 
AAV-222876
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SGTB.

AAV-222876
AAV-h-SGTB

Ready-to-use AAV expressing Human SGTB (small glutamine rich tetratricopeptide repeat containing beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
beta-SGT; SGT2; small glutamine rich protein with tetratricopeptide repeats 2; Small glutamine-rich protein with tetratricopeptide repeats 2; small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; small glutamine-rich tetratricopeptide repeat-containing protein beta
Description (eCommerce)
Nuclear prelamin A recognition factor-like protein (NARFL) is a component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. NARFL seems to negatively regulate the level of HIF1A expression, although this effect could be indirect [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6Q4].
Gene ID
54557
Gene Name (eCommerce)
small glutamine rich tetratricopeptide repeat containing beta
Gene Name (Vector)
small glutamine rich tetratricopeptide repeat containing beta
Gene Symbol
SGTB
HGNC ID
HGNC:23567
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
915
ORF Size (bp)
915 bp
Protein Name (eCommerce)
Small glutamine-rich tetratricopeptide repeat-containing protein beta
RefSeq ID
NM_019072
RefSeq Synonyms
NM_019072, BC012044,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Nuclear prelamin A recognition factor-like protein (NARFL) is a component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. NARFL seems to negatively regulate the level of HIF1A expression, although this effect could be indirect [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H6Q4].
UniGene ID
Hs.482301
UniProt ID (eCommerce)
Q96EQ0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.