human SEPT11 Over-expression AAV

Name 
AAV-h-SEPT11
Cat No 
AAV-222598
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SEPT11.

AAV-222598
AAV-h-SEPT11

Ready-to-use AAV expressing Human SEPT11 (septin 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; septin-11
Description (eCommerce)
Septin 11 is a filament-forming cytoskeletal GTPase. Septin 11 may play a role in cytokinesis (Potential). It also may play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NVA2].
Description (Vector)
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 (PubMed 15196925); Nagata et al., 2004 (PubMed 15485874)).(supplied by OMIM, Jul 2009)
Gene ID
55752
Gene Name (eCommerce)
septin 11
Gene Name (Vector)
septin 11
Gene Symbol
11-Sep
HGNC ID
HGNC:25589
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
Protein Name (eCommerce)
Septin-11
RefSeq ID
NM_018243
RefSeq Synonyms
NM_018243, NM_001306147, BC063615, BC008083,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Neurobiology,Synapse
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,neurobiology
Species
human
Target Sentence
Septin 11 is a filament-forming cytoskeletal GTPase. Septin 11 may play a role in cytokinesis (Potential). It also may play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NVA2].
UniGene ID
Hs.128199
UniProt ID (eCommerce)
Q9NVA2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.