human SEMA3F Over-expression AAV

Name 
AAV-h-SEMA3F
Cat No 
AAV-222545
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SEMA3F.

AAV-222545
AAV-h-SEMA3F

Ready-to-use AAV expressing Human SEMA3F (semaphorin 3F). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SEMA-IV; SEMA4; SEMAK
Description (Vector)
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 (PubMed 8269517)). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 (PubMed 8402908)) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 (PubMed 7637782)), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.(supplied by OMIM, Mar 2008)
Gene ID
6405
Gene Name (Vector)
semaphorin 3F
Gene Symbol
SEMA3F
HGNC ID
HGNC:10728
ORF Size (aa)
2358
ORF Size (bp)
2358 bp
RefSeq ID
NM_004186
RefSeq Synonyms
NM_004186, NM_001318800, NM_001318798, BC042914,
Species
human
UniGene ID
Hs.32981

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.