human SEL1L Over-expression AAV

Name 
AAV-h-SEL1L
Cat No 
AAV-222515
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SEL1L.

AAV-222515
AAV-h-SEL1L

Ready-to-use AAV expressing Human SEL1L (SEL1L ERAD E3 ligase adaptor subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PRO1063; SEL1-LIKE; SEL1L1
Description (Vector)
SEL1L is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6400
Gene Name (Vector)
SEL1L ERAD E3 ligase adaptor subunit
Gene Symbol
SEL1L
HGNC ID
HGNC:10717
ORF Size (aa)
2385
ORF Size (bp)
2385 bp
RefSeq ID
NM_005065
RefSeq Synonyms
NM_005065, NM_001244984, BC172577, BC172282,
Species
human
UniGene ID
Hs.181300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.