human SEC24C Over-expression AAV

Name 
AAV-h-SEC24C
Cat No 
AAV-222492
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SEC24C.

AAV-222492
AAV-h-SEC24C

Ready-to-use AAV expressing Human SEC24C (SEC24 homolog C, COPII coat complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
protein transport protein Sec24C; SEC24 family, member C; SEC24 related gene family, member C; SEC24-related protein C
Description (eCommerce)
SEC24-related protein C (SEC24C) is a component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53992].
Description (Vector)
SEC24C is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
9632
Gene Name (eCommerce)
SEC24 homolog C, COPII coat complex component
Gene Name (Vector)
SEC24 homolog C, COPII coat complex component
Gene Symbol
SEC24C
HGNC ID
HGNC:10705
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3285
ORF Size (bp)
3285 bp
Protein Name (eCommerce)
Protein transport protein Sec24C
RefSeq ID
NM_004922
RefSeq Synonyms
NM_198597, NM_004922, BC018928,
Research Areas
Antigen Processing and Presentation,Golgi Apparatus,Immunology,Metabolism/Metabolic Process,Signal Transduction,Translational Control,Transport
Research Areas (Faceted)
cell_biology,immunology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
SEC24-related protein C (SEC24C) is a component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P53992].
UniGene ID
Hs.81964
UniProt ID (eCommerce)
P53992

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.