human SCNN1B Over-expression AAV

Name 
AAV-h-SCNN1B
Cat No 
AAV-222378
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SCNN1B.

AAV-222378
AAV-h-SCNN1B

Ready-to-use AAV expressing Human SCNN1B (sodium channel epithelial 1 beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BESC1; ENaCb; ENaCbeta; SCNEB
Description (Vector)
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
Gene ID
6338
Gene Name (Vector)
sodium channel epithelial 1 beta subunit
Gene Symbol
SCNN1B
HGNC ID
HGNC:10600
ORF Size (aa)
1923
ORF Size (bp)
1923 bp
RefSeq ID
NM_000336
RefSeq Synonyms
NM_000336, BC036352,
Species
human
UniGene ID
Hs.414614

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.