human SAP18 Over-expression AAV

Name 
AAV-h-SAP18
Cat No 
AAV-222234
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SAP18.

AAV-222234
AAV-h-SAP18

Ready-to-use AAV expressing Human SAP18 (Sin3A associated protein 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2HOR0202; SAP18P
Description (Vector)
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
Gene ID
10284
Gene Name (Vector)
Sin3A associated protein 18
Gene Symbol
SAP18
HGNC ID
HGNC:10530
ORF Size (aa)
462
RefSeq ID
NM_005870
RefSeq Synonyms
NM_005870, BC030836,
Species
human
UniGene ID
Hs.524899

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.