human RRBP1 Over-expression AAV

Name 
AAV-h-RRBP1
Cat No 
AAV-221996
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RRBP1.

AAV-221996
AAV-h-RRBP1

Ready-to-use AAV expressing Human RRBP1 (ribosome binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
180 kDa ribosome receptor homolog; ES/130; ES/130-related protein; ES130; hES; ribosome binding protein 1 homolog 180kDa (dog); ribosome receptor protein; ribosome-binding protein 1; RRp
Description (eCommerce)
Ribosome binding protein 1 (RRBP1) is a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this protein plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions [taken from NCBI Entrez Gene (Gene ID: 6238)].
Description (Vector)
RRBP1 encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
Gene ID
6238
Gene Name (eCommerce)
ribosome binding protein 1
Gene Name (Vector)
ribosome binding protein 1
Gene Symbol
RRBP1
HGNC ID
HGNC:10448
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2805
ORF Size (bp)
2805 bp
Protein Name (eCommerce)
Ribosome-binding protein 1
RefSeq ID
NM_004587
RefSeq Synonyms
NM_004587, NM_001042576, BC128578, BC128577,
Research Areas
Signal Transduction,Translational Control,Transport
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Ribosome binding protein 1 (RRBP1) is a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this protein plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions [taken from NCBI Entrez Gene (Gene ID: 6238)].
UniGene ID
Hs.472213
UniProt ID (eCommerce)
Q9P2E9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.