human RPRD1B Over-expression AAV

Name 
AAV-h-RPRD1B
Cat No 
AAV-221801
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RPRD1B.

AAV-221801
AAV-h-RPRD1B

Ready-to-use AAV expressing Human RPRD1B (regulation of nuclear pre-mRNA domain containing 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C20orf77; Cell cycle-related and expression-elevated protein in tumor; cell-cycle related and expression-elevated protein in tumor; CREPT; dJ1057B20.2; K-H; Ku70-binding protein 5-Hera; Kub5-Hera; NET60; regulation of nuclear pre-mRNA domain-containing protein 1B
Description (eCommerce)
RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. RPRD1B is a transcriptional regulator that promotes cell proliferation and enhances the transcription of a number of cell cycle-related genes including CCND1, CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQG5].
Gene ID
58490
Gene Name (eCommerce)
regulation of nuclear pre-mRNA domain containing 1B
Gene Name (Vector)
regulation of nuclear pre-mRNA domain containing 1B
Gene Symbol
RPRD1B
HGNC ID
HGNC:16209
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
981
ORF Size (bp)
981 bp
Protein Name (eCommerce)
Regulation of nuclear pre-mRNA domain-containing protein 1B
RefSeq ID
NM_021215
RefSeq Synonyms
NM_021215, BC033629,
Research Areas
Cell Cycle,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. RPRD1B is a transcriptional regulator that promotes cell proliferation and enhances the transcription of a number of cell cycle-related genes including CCND1, CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQG5].
UniGene ID
Hs.278839
UniProt ID (eCommerce)
Q9NQG5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.