human RPN1 Over-expression AAV

Name 
AAV-h-RPN1
Cat No 
AAV-221787
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RPN1.

AAV-221787
AAV-h-RPN1

Ready-to-use AAV expressing Human RPN1 (ribophorin I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); OST1; RBPH1; Ribophorin I; ribophorin-1; RPN-I
Description (eCommerce)
Ribophorin I is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains [taken from NCBI Entrez Gene (Gene ID: 6184)].
Description (Vector)
RPN1 encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.
Gene ID
6184
Gene Name (eCommerce)
ribophorin I
Gene Name (Vector)
ribophorin I
Gene Symbol
RPN1
HGNC ID
HGNC:10381
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1824
ORF Size (bp)
1824 bp
Protein Name (eCommerce)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
RefSeq ID
NM_002950
RefSeq Synonyms
NM_002950, BC010839,
Research Areas
Complexome,Gene Expression,Metabolism/Metabolic Process,Proteasome,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Ribophorin I is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains [taken from NCBI Entrez Gene (Gene ID: 6184)].
UniGene ID
Hs.603636
UniProt ID (eCommerce)
P04843

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.