human RIOK2 Over-expression AAV

Name 
AAV-h-RIOK2
Cat No 
AAV-221250
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RIOK2.

AAV-221250
AAV-h-RIOK2

Ready-to-use AAV expressing Human RIOK2 (RIO kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RIO kinase 2; RIO2; serine/threonine-protein kinase RIO2
Description (eCommerce)
RIO kinase 2 (RIOK2) is a member of the RIO family of atypical serine protein kinases first characterized in yeast. There are three RIO kinase subfamilies: RIO1, RIO2, and RIO3. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. Studies of RIO kinases in yeast indicate that they play a role in ribosome biogenesis. Human RIOK2 has been shown to be a part of a late 40S pre-ribosomal particle and have influence on 40S maturation.
Gene ID
55781
Gene Name (eCommerce)
RIO kinase 2
Gene Name (Vector)
RIO kinase 2
Gene Symbol
RIOK2
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1659
ORF Size (bp)
1659 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase RIO2
RefSeq ID
NM_018343
RefSeq Synonyms
NM_018343, NM_001159749, BC000953,
Research Areas
Cell Cycle,Kinase/Phosphatase,RNA Processing,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
RIO kinase 2 (RIOK2) is a member of the RIO family of atypical serine protein kinases first characterized in yeast. There are three RIO kinase subfamilies: RIO1, RIO2, and RIO3. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. Studies of RIO kinases in yeast indicate that they play a role in ribosome biogenesis. Human RIOK2 has been shown to be a part of a late 40S pre-ribosomal particle and have influence on 40S maturation.
UniGene ID
Hs.594978
UniProt ID (eCommerce)
Q9BVS4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.