human RILPL1 Over-expression AAV

Name 
AAV-h-RILPL1
Cat No 
AAV-221230
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RILPL1.

AAV-221230
AAV-h-RILPL1

Ready-to-use AAV expressing Human RILPL1 (Rab interacting lysosomal protein like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GAPDH competitor of SIAH protein enhances life; GOSPEL; Rab-interacting lysosomal-like protein 1; RILP-like protein 1; RLP1
Description (eCommerce)
RILP-like protein 1, encoded for by the gene RILPL1, plays a role in the regulation of cell shape and polarity as well as cellular protein transport. RILPL1 is a neuroprotective protein - sequestering GAPDH in the cytosol thereby preventing the apoptotic function of GAPDH in the nucleus [taken from UniProtKB (Entry: Q5EBL4)].
Gene ID
353116
Gene Name (eCommerce)
Rab interacting lysosomal protein like 1
Gene Name (Vector)
Rab interacting lysosomal protein like 1
Gene Symbol
RILPL1
HGNC ID
HGNC:26814
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
ORF Size (bp)
759 bp
Protein Name (eCommerce)
RILP-like protein 1
RefSeq ID
NM_178314
RefSeq Synonyms
NM_178314, NM_001319302, NM_001319244, NM_001319243, BC089444, BC080626,
Research Areas
Apoptosis,Cytoskeleton,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
RILP-like protein 1, encoded for by the gene RILPL1, plays a role in the regulation of cell shape and polarity as well as cellular protein transport. RILPL1 is a neuroprotective protein - sequestering GAPDH in the cytosol thereby preventing the apoptotic function of GAPDH in the nucleus [taken from UniProtKB (Entry: Q5EBL4)].
UniGene ID
Hs.530315
UniProt ID (eCommerce)
Q5EBL4

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.