human RCN1 Over-expression AAV

Name 
AAV-h-RCN1
Cat No 
AAV-220946
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RCN1.

AAV-220946
AAV-h-RCN1

Ready-to-use AAV expressing Human RCN1 (reticulocalbin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory protein Li 84; HEL-S-84; PIG20; proliferation-inducing gene 20; RCAL; RCN; reticulocalbin 1, EF-hand calcium binding domain; reticulocalbin-1
Description (eCommerce)
Reticulocalbin-1 is a member of the CREC (Cab45/reticulocalbin/ERC45/calumenin) family of calcium binding proteins. Reticulocalbin-1 localizes to the lumen of the endoplasmic reticulum (ER) and may function to regulate calcium-dependent activities in the ER.
Description (Vector)
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Gene ID
5954
Gene Name (eCommerce)
reticulocalbin 1
Gene Name (Vector)
reticulocalbin 1
Gene Symbol
RCN1
HGNC ID
HGNC:9934
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
Protein Name (eCommerce)
Reticulocalbin-1
RefSeq ID
NM_002901
RefSeq Synonyms
NM_002901, BC010120,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Reticulocalbin-1 is a member of the CREC (Cab45/reticulocalbin/ERC45/calumenin) family of calcium binding proteins. Reticulocalbin-1 localizes to the lumen of the endoplasmic reticulum (ER) and may function to regulate calcium-dependent activities in the ER.
UniGene ID
Hs.97887
UniProt ID (eCommerce)
Q15293

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.