human RBX1 Over-expression AAV

Name 
AAV-h-RBX1
Cat No 
AAV-220928
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RBX1.

AAV-220928
AAV-h-RBX1

Ready-to-use AAV expressing Human RBX1 (ring-box 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BA554C12.1; E3 ubiquitin-protein ligase RBX1; E3 ubiquitin-protein transferase RBX1; Protein ZYP; Rbx1; regulator of cullins 1; RING finger protein 75; ring-box 1, E3 ubiquitin protein ligase; RING-box protein 1; RNF75; ROC1; ZYP protein
Description (eCommerce)
ROC1 (regulator of cullins 1) is also known as RBX1 (ring-box 1 E3 ubiquitin protein ligase). ROC1 interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression.
Description (Vector)
This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.
Gene ID
9978
Gene Name (eCommerce)
ring-box 1
Gene Name (Vector)
ring-box 1
Gene Symbol
RBX1
HGNC ID
HGNC:9928
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
327
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RBX1
RefSeq ID
NM_014248
RefSeq Synonyms
NM_014248, BC001466,
Research Areas
Antigen Processing and Presentation,Cancer,Cell Cycle,Cytokine Signaling,DNA Damage/Repair,HIF-1 Signaling,Host-Virus Interactions,Hypoxia,Immunology,Interleukin Signaling,Kidney Cancer,Meiosis,Notch Signaling,Prolactin Signaling,Signal Transduction,TGF-beta Signaling,Ubiquitination,Wnt Signaling,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,signal_transduction,transcription_translation
Species
human
Target Sentence
ROC1 (regulator of cullins 1) is also known as RBX1 (ring-box 1 E3 ubiquitin protein ligase). ROC1 interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression.
UniGene ID
Hs.474949
UniProt ID (eCommerce)
P62877

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.