human RBAK Over-expression AAV

Name 
AAV-h-RBAK
Cat No 
AAV-220822
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RBAK.

AAV-220822
AAV-h-RBAK

Ready-to-use AAV expressing Human RBAK (RB associated KRAB zinc finger). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ZNF769
Description (Vector)
RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
Gene ID
57786
Gene Name (Vector)
RB associated KRAB zinc finger
Gene Symbol
RBAK
HGNC ID
HGNC:17680
ORF Size (aa)
2145
ORF Size (bp)
2145 bp
RefSeq ID
NM_021163
RefSeq Synonyms
NM_021163, NM_001204456, BC136676, BC136675,
Species
human
UniGene ID
Hs.396178

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.