human RABEP1 Over-expression AAV

Name 
AAV-h-RABEP1
Cat No 
AAV-220599
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RABEP1.

AAV-220599
AAV-h-RABEP1

Ready-to-use AAV expressing Human RABEP1 (rabaptin, RAB GTPase binding effector protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
neurocrescin; rab GTPase-binding effector protein 1; RAB5EP; rabaptin-4; rabaptin-5; rabaptin-5alpha; RABPT5; renal carcinoma antigen NY-REN-17
Description (eCommerce)
RAB GTPase binding effector protein 1 (RABEP1) is a Rab effector protein and acts as a linker between gamma-adaptin, RAB4A and RAB5A. It stimulates RABGEF1 mediated nucleotide exchange on RAB5A RABEP1 and is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15276].
Gene ID
9135
Gene Name (eCommerce)
rabaptin, RAB GTPase binding effector protein 1
Gene Name (Vector)
rabaptin, RAB GTPase binding effector protein 1
Gene Symbol
RABEP1
HGNC ID
HGNC:17677
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2589
ORF Size (bp)
2589 bp
Protein Name (eCommerce)
Rab GTPase-binding effector protein 1
RefSeq ID
NM_004703
RefSeq Synonyms
NM_004703, NM_001291582, NM_001291581, NM_001083585, BC041700,
Research Areas
Apoptosis,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RAB GTPase binding effector protein 1 (RABEP1) is a Rab effector protein and acts as a linker between gamma-adaptin, RAB4A and RAB5A. It stimulates RABGEF1 mediated nucleotide exchange on RAB5A RABEP1 and is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15276].
UniGene ID
Hs.592121
UniProt ID (eCommerce)
Q15276

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.