human PUM2 Over-expression AAV

Name 
AAV-h-PUM2
Cat No 
AAV-220394
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PUM2.

AAV-220394
AAV-h-PUM2

Ready-to-use AAV expressing Human PUM2 (pumilio RNA binding family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PUMH2; pumilio homolog 2; pumilio-2; PUML2
Description (eCommerce)
Pumilio 2 is a germline specific RNA binding protein that functions as a translational regulator by binding 3’ UTR elements. Pumilio 2 and its homolog Pumiolio 1 are highly evolutionarily conserved proteins that appear to function in germline maintenance. Pumilio 2 has been shown to interact with DAZL, a protein required for germ cell development.
Gene ID
23369
Gene Name (eCommerce)
pumilio RNA binding family member 2
Gene Name (Vector)
pumilio RNA binding family member 2
Gene Symbol
PUM2
HGNC ID
HGNC:14958
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3195
ORF Size (bp)
3195 bp
Protein Name (eCommerce)
Pumilio homolog 2
RefSeq ID
NM_015317
RefSeq Synonyms
NM_015317, NM_001282791, NM_001282790, NM_001282752, BC143550, BC112048, BC112046,
Research Areas
RNA Binding,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Pumilio 2 is a germline specific RNA binding protein that functions as a translational regulator by binding 3’ UTR elements. Pumilio 2 and its homolog Pumiolio 1 are highly evolutionarily conserved proteins that appear to function in germline maintenance. Pumilio 2 has been shown to interact with DAZL, a protein required for germ cell development.
UniGene ID
Hs.467824
UniProt ID (eCommerce)
Q8TB72

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.