human PTPRN2 Over-expression AAV

Name 
AAV-h-PTPRN2
Cat No 
AAV-220355
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PTPRN2.

AAV-220355
AAV-h-PTPRN2

Ready-to-use AAV expressing Human PTPRN2 (protein tyrosine phosphatase, receptor type N2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2
Description (Vector)
PTPRN2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Gene ID
5799
Gene Name (Vector)
protein tyrosine phosphatase, receptor type N2
Gene Symbol
PTPRN2
HGNC ID
HGNC:9677
ORF Size (aa)
1902
ORF Size (bp)
1902 bp
RefSeq ID
NM_002847
RefSeq Synonyms
NM_130843, NM_130842, NM_002847, NM_001308268, NM_001308267, BC071570, BC034040,
Species
human
UniGene ID
Hs.716042

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.