human PTPRN Over-expression AAV

Name 
AAV-h-PTPRN
Cat No 
AAV-220354
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PTPRN.

AAV-220354
AAV-h-PTPRN

Ready-to-use AAV expressing Human PTPRN (protein tyrosine phosphatase, receptor type N). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
Description (Vector)
PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Gene ID
5798
Gene Name (Vector)
protein tyrosine phosphatase, receptor type N
Gene Symbol
PTPRN
HGNC ID
HGNC:9676
ORF Size (aa)
2853
ORF Size (bp)
2853 bp
RefSeq ID
NM_002846
RefSeq Synonyms
NM_002846, NM_001199764, NM_001199763, BC070053, BC007713,
Species
human
UniGene ID
Hs.89655

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.