human PSMD14 Over-expression AAV

Name 
AAV-h-PSMD14
Cat No 
AAV-220154
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PSMD14.

AAV-220154
AAV-h-PSMD14

Ready-to-use AAV expressing Human PSMD14 (proteasome 26S subunit, non-ATPase 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
26S proteasome non-ATPase regulatory subunit 14; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated PAD1 homolog 1; PAD1; POH1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; RPN11; testis tissue sperm-binding protein Li 69n
Description (eCommerce)
PSMD14 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 14] is a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. PSMD14 is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination [taken from NCBI Entrez Gene (Gene ID: 10213)].
Description (Vector)
PSMD14 encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.
Gene ID
10213
Gene Name (eCommerce)
proteasome 26S subunit, non-ATPase 14
Gene Name (Vector)
proteasome 26S subunit, non-ATPase 14
Gene Symbol
PSMD14
HGNC ID
HGNC:16889
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
933
Protein Name (eCommerce)
26S proteasome non-ATPase regulatory subunit 14
RefSeq ID
NM_005805
RefSeq Synonyms
NM_005805, BC066336,
Research Areas
Antigen Processing and Presentation,Apoptosis,Cell Cycle,Cell Division,Complexome,DNA Damage/Repair,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,Neurobiology,Neurodegeneration,Parkinson's Disease,Parkin-Ubiquitin Proteasomal System,Proteasome,RNA Processing,Ubiquitination
Research Areas (Faceted)
cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism,neurobiology,cell_biology
Species
human
Target Sentence
PSMD14 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 14] is a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. PSMD14 is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination [taken from NCBI Entrez Gene (Gene ID: 10213)].
UniGene ID
Hs.567410
UniProt ID (eCommerce)
O00487

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.