human PRPF6 Over-expression AAV

Name 
AAV-h-PRPF6
Cat No 
AAV-219963
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PRPF6.

AAV-219963
AAV-h-PRPF6

Ready-to-use AAV expressing Human PRPF6 (pre-mRNA processing factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
androgen receptor N-terminal domain transactivating protein-1; Androgen receptor N-terminal domain-transactivating protein 1; ANT1; ANT-1; C20orf14; hPrp6; p102 U5 small nuclear ribonucleoprotein particle-binding protein; pre-mRNA-processing factor 6; Prp6; PRP6 homolog; PRP6 pre-mRNA processing factor 6 homolog; putative mitochondrial outer membrane protein import receptor; RP60; SNRNP102; TOM; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein; U5-102K
Description (eCommerce)
Pre-mRNA-processing factor 6 (PRP6) is involved in pre-mRNA splicing. PRP6 may act in the tri-snRNP complex as a bridging factor between U5 and U4/U6 snRNPs in the late step of spliceosome assembly. It may be necessary for tri-snRNP formation [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/O94906].
Description (Vector)
PRPF6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
Gene ID
24148
Gene Name (eCommerce)
pre-mRNA processing factor 6
Gene Name (Vector)
pre-mRNA processing factor 6
Gene Symbol
PRPF6
HGNC ID
HGNC:15860
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2826
ORF Size (bp)
2826 bp
Protein Name (eCommerce)
Pre-mRNA-processing factor 6
RefSeq ID
NM_012469
RefSeq Synonyms
NM_012469, BC001666,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Pre-mRNA-processing factor 6 (PRP6) is involved in pre-mRNA splicing. PRP6 may act in the tri-snRNP complex as a bridging factor between U5 and U4/U6 snRNPs in the late step of spliceosome assembly. It may be necessary for tri-snRNP formation [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/O94906].
UniGene ID
Hs.31334
UniProt ID (eCommerce)
O94906

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.