human PRPF18 Over-expression AAV

Name
AAV-h-PRPF18

Cat No
AAV-219946

Availability
4-5 weeks

This is an AAV expressing Human PRPF18.

AAV-219946

AAV-h-PRPF18

Ready-to-use AAV expressing Human PRPF18 (pre-mRNA processing factor 18). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hPrp18; PRP18

Description (Vector)

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.

Gene ID

8559

Gene Name (Vector)

pre-mRNA processing factor 18

Gene Symbol

PRPF18

HGNC ID

HGNC:17351

ORF Size (aa)

1029

ORF Size (bp)

1029 bp

RefSeq ID

NM_003675

RefSeq Synonyms

NM_003675, BC000794,

Species

human

UniGene ID

Hs.161181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.