human PRKAG2 Over-expression AAV
This is an AAV expressing Human PRKAG2.
AAV-219846
AAV-h-PRKAG2
Ready-to-use AAV expressing Human PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AAKG; AAKG2; CMH6; H91620p; WPWS
Description (Vector)
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
51422
Gene Name (Vector)
protein kinase AMP-activated non-catalytic subunit gamma 2
Gene Symbol
PRKAG2
HGNC ID
HGNC:9386
ORF Size (aa)
1578
ORF Size (bp)
1578 bp
RefSeq ID
NM_016203
RefSeq Synonyms
NM_024429, NM_016203, NM_001304531, NM_001304527, NM_001040633, BC068598, BC020540,
Species
human
UniGene ID
Hs.647072
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.