human PPP1R10 Over-expression AAV

Name
AAV-h-PPP1R10

Cat No
AAV-219602

Availability
4-5 weeks

This is an AAV expressing Human PPP1R10.

AAV-219602

AAV-h-PPP1R10

Ready-to-use AAV expressing Human PPP1R10 (protein phosphatase 1 regulatory subunit 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAT53; FB19; HLA-C associated transcript 53; MHC class I region proline-rich protein CAT53; p99; phosphatase 1 nuclear targeting subunit; PNUTS; PP1-binding protein of 114 kDa; PP1R10; Protein FB19; protein phosphatase 1, regulatory (inhibitor) subunit 10; R111; serine/threonine-protein phosphatase 1 regulatory subunit 10; testis tissue sperm-binding protein Li 67n

Description (eCommerce)

PNUTS (PP1 nuclear targeting subunit) is a regulatory subunit of the PP1 protein phosphatase, a serine/threonine phosphatase involved in mitotic exit and chromosome decondensation. PNUTS has been shown to play a role in targeting PP1 to the nucleus and mediating PP1 association to specific RNAs.

Description (Vector)

PPP1R10 encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. PPP1R10 lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene.

Gene ID

5514

Gene Name (eCommerce)

protein phosphatase 1 regulatory subunit 10

Gene Name (Vector)

protein phosphatase 1 regulatory subunit 10

Gene Symbol

PPP1R10

HGNC ID

HGNC:9284

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2823

ORF Size (bp)

2823 bp

Protein Name (eCommerce)

Serine/threonine-protein phosphatase 1 regulatory subunit 10

RefSeq ID

NM_002714

RefSeq Synonyms

NM_002714, BC136294,

Research Areas

Kinase/Phosphatase,Nuclear Import/Export,RNA Binding,Transcription Factor/Regulator,Transport,Zinc-finger

Research Areas (Faceted)

cell_biology,signal_transduction,transcription_translation

Species

human

Target Sentence

UniGene ID

Hs.106019

UniProt ID (eCommerce)

Q96QC0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.