human PPP1CA Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219596
Availability:
3-5 weeks
Name:
AAV-h-PPP1CA
This is an AAV expressing Human PPP1CA.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PPP1CA
- Gene Name
- protein phosphatase 1 catalytic subunit alpha
- Gene ID
- 5499
- Gene Synonyms
- PP-1A; PP1A; PP1alpha; PPP1A
- ORF Size
- 993 bp
- RefSeq#
- BC004482
- Gene Description
- PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.183994
- HGNC ID
- HGNC:9281
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