human POR Over-expression AAV

Name 
AAV-h-POR
Cat No 
AAV-219453
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POR.

AAV-219453
AAV-h-POR

Ready-to-use AAV expressing Human POR (cytochrome p450 oxidoreductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CPR; CYPOR; P450R
Description (Vector)
POR encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Gene ID
5447
Gene Name (Vector)
cytochrome p450 oxidoreductase
Gene Symbol
POR
HGNC ID
HGNC:9208
ORF Size (aa)
2043
ORF Size (bp)
2043 bp
RefSeq ID
NM_000941
RefSeq Synonyms
NM_000941, BC034277,
Species
human
UniGene ID
Hs.354056

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.