human POLR1D Over-expression AAV

Name 
AAV-h-POLR1D
Cat No 
AAV-219382
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human POLR1D.

AAV-219382
AAV-h-POLR1D

Ready-to-use AAV expressing Human POLR1D (RNA polymerase I subunit D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AC19; DNA-directed RNA polymerase I subunit D; DNA-directed RNA polymerases I and III subunit RPAC2; hRPA19; POLR1C; polymerase (RNA) I polypeptide D, 16kDa; polymerase (RNA) I subunit D; Protein POLR1D; RNA polymerase I 16 kDa subunit; RNA polymerase I subunit D; RNA polymerases I and III subunit AC2; RPA16; RPA9; RPAC2; RPC16; RPO1-3; TCS2
Description (eCommerce)
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in the POLR1D gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder [taken from NCBI Entrez Gene (Gene ID: 51082)].
Description (Vector)
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
Gene ID
51082
Gene Name (eCommerce)
RNA polymerase I and III subunit D
Gene Name (Vector)
RNA polymerase I subunit D
Gene Symbol
POLR1D
HGNC ID
HGNC:20422
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
402
Protein Name (eCommerce)
DNA-directed RNA polymerases I and III subunit RPAC2;Protein POLR1D, isoform 2
RefSeq ID
NM_015972
RefSeq Synonyms
NM_152705, NM_015972, NM_001206559, BC018528, BC015319, BC000889,
Research Areas
Cancer,Epigenetic Regulation of Gene Expression,Gene Expression,Host-Virus Interactions,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cancer,cell_biology,genetics,infectious_disease,signal_transduction
Species
human
Target Sentence
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in the POLR1D gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder [taken from NCBI Entrez Gene (Gene ID: 51082)].
UniGene ID
Hs.507584
UniProt ID (eCommerce)
P0DPB6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.