human PLS3 Over-expression AAV

Name 
AAV-h-PLS3
Cat No 
AAV-219227
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLS3.

AAV-219227
AAV-h-PLS3

Ready-to-use AAV expressing Human PLS3 (plastin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BMND18; T-plastin
Description (Vector)
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.
Gene ID
5358
Gene Name (Vector)
plastin 3
Gene Symbol
PLS3
HGNC ID
HGNC:9091
ORF Size (aa)
1893
ORF Size (bp)
1893 bp
RefSeq ID
NM_005032
RefSeq Synonyms
NM_005032, NM_001282338, NM_001282337, NM_001172335, NM_001136025, BC056898, BC039049,
Species
human
UniGene ID
Hs.496622

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.