human PJA1 Over-expression AAV

Name
AAV-h-PJA1

Cat No
AAV-219016

Availability
4-5 weeks

This is an AAV expressing Human PJA1.

AAV-219016

AAV-h-PJA1

Ready-to-use AAV expressing Human PJA1 (praja ring finger ubiquitin ligase 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PRAJA1; RNF70

Description (Vector)

PJA1 encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. PJA1 is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants.

Gene ID

64219

Gene Name (Vector)

praja ring finger ubiquitin ligase 1

Gene Symbol

PJA1

HGNC ID

HGNC:16648

ORF Size (aa)

1932

ORF Size (bp)

1932 bp

RefSeq ID

NM_022368

RefSeq Synonyms

NM_145119, NM_022368, NM_001032396, BC105053, BC105051, BC075803,

Species

human

UniGene ID

Hs.522679

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.