human PIGM Over-expression AAV

Name 
AAV-h-PIGM
Cat No 
AAV-218912
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PIGM.

AAV-218912
AAV-h-PIGM

Ready-to-use AAV expressing Human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPI-MT-I
Description (Vector)
PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGM encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.
Gene ID
93183
Gene Name (Vector)
phosphatidylinositol glycan anchor biosynthesis class M
Gene Symbol
PIGM
HGNC ID
HGNC:18858
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_145167
RefSeq Synonyms
NM_145167, BC019865, BC001803,
Species
human
UniGene ID
Hs.552810

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.