human PI3 Over-expression AAV
This is an AAV expressing Human PI3.
AAV-218879
AAV-h-PI3
Ready-to-use AAV expressing Human PI3 (peptidase inhibitor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cementoin; ESI; SKALP; WAP3; WFDC14
Description (Vector)
PI3 encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
Gene ID
5266
Gene Name (Vector)
peptidase inhibitor 3
Gene Symbol
PI3
HGNC ID
HGNC:8947
ORF Size (aa)
354
RefSeq ID
NM_002638
RefSeq Synonyms
NM_002638, BC010952,
Species
human
UniGene ID
Hs.112341
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.