human PGP Over-expression AAV

Name 
AAV-h-PGP
Cat No 
AAV-218767
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PGP.

AAV-218767
AAV-h-PGP

Ready-to-use AAV expressing Human PGP (phosphoglycolate phosphatase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
aspartate-based ubiquitous Mg(2+)-dependent phosphatase; AUM; G3PP; glycerol-3-phosphate phosphatase; PGP; PGPase; Phosphoglycolate phosphatase
Description (eCommerce)
Glycerol-3-phosphate phosphatase (PGP) hydrolyzes glycerol-3-phosphate into glycerol. It regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Has been shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A6NDG6].
Gene ID
283871
Gene Name (eCommerce)
phosphoglycolate phosphatase
Gene Name (Vector)
phosphoglycolate phosphatase
Gene Symbol
PGP
HGNC ID
HGNC:8909
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
966
ORF Size (bp)
966 bp
Protein Name (eCommerce)
Glycerol-3-phosphate phosphatase
RefSeq ID
NM_001042371
RefSeq Synonyms
NM_001042371, BC157035, BC156305,
Research Areas
Kinase/Phosphatase,Metabolism/Metabolic Process,Phosphatase
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Glycerol-3-phosphate phosphatase (PGP) hydrolyzes glycerol-3-phosphate into glycerol. It regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Has been shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/A6NDG6].
UniGene ID
Hs.442634
UniProt ID (eCommerce)
A6NDG6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.