human PEX12 Over-expression AAV

Name 
AAV-h-PEX12
Cat No 
AAV-218636
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PEX12.

AAV-218636
AAV-h-PEX12

Ready-to-use AAV expressing Human PEX12 (peroxisomal biogenesis factor 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PAF-3; PBD3A
Description (Vector)
PEX12 belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).
Gene ID
5193
Gene Name (Vector)
peroxisomal biogenesis factor 12
Gene Symbol
PEX12
HGNC ID
HGNC:8854
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_000286
RefSeq Synonyms
NM_000286, BC031085,
Species
human
UniGene ID
Hs.591190

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.