human PDLIM3 Over-expression AAV

Name
AAV-h-PDLIM3

Cat No
AAV-218544

Availability
4-5 weeks

This is an AAV expressing Human PDLIM3.

AAV-218544

AAV-h-PDLIM3

Ready-to-use AAV expressing Human PDLIM3 (PDZ and LIM domain 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ALP

Description (Vector)

PDLIM3 contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

Gene ID

27295

Gene Name (Vector)

PDZ and LIM domain 3

Gene Symbol

PDLIM3

HGNC ID

HGNC:20767

ORF Size (aa)

951

ORF Size (bp)

951 bp

RefSeq ID

NM_014476

RefSeq Synonyms

NM_014476, NM_001257963, NM_001257962, NM_001114107, BC027870,

Species

human

UniGene ID

Hs.85862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.