human PDK2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-218535
Availability:
3-5 weeks
Name:
AAV-h-PDK2
This is an AAV expressing Human PDK2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PDK2
- Gene Name
- pyruvate dehydrogenase kinase 2
- Gene ID
- 5164
- Gene Synonyms
- PDHK2; PDKII
- ORF Size
- 1224 bp
- RefSeq#
- BC040478
- Gene Description
- PDK2 encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniGene ID
- Hs.256667
- HGNC ID
- HGNC:8810
Related Products
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