human PCOLCE Over-expression AAV

Name
AAV-h-PCOLCE

Cat No
AAV-218399

Availability
4-5 weeks

This is an AAV expressing Human PCOLCE.

AAV-218399

AAV-h-PCOLCE

Ready-to-use AAV expressing Human PCOLCE (procollagen C-endopeptidase enhancer). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PCPE; PCPE-1; PCPE1

Description (Vector)

Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.

Gene ID

5118

Gene Name (Vector)

procollagen C-endopeptidase enhancer

Gene Symbol

PCOLCE

HGNC ID

HGNC:8738

ORF Size (aa)

1350

ORF Size (bp)

1350 bp

RefSeq ID

NM_002593

RefSeq Synonyms

NM_002593, BC033205, BC000574,

Species

human

UniGene ID

Hs.202097

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.