human PCK1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-218382
Availability:
3-5 weeks
Name:
AAV-h-PCK1
This is an AAV expressing Human PCK1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PCK1
- Gene Name
- phosphoenolpyruvate carboxykinase 1
- Gene ID
- 5105
- Gene Synonyms
- PEPCK-C; PEPCK1; PEPCKC
- ORF Size
- 1869 bp
- RefSeq#
- BC023978
- Gene Description
- PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
- UniGene ID
- Hs.1872
- HGNC ID
- HGNC:8724
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