human PCDH8 Over-expression AAV

Name
AAV-h-PCDH8

Cat No
AAV-218331

Availability
4-5 weeks

This is an AAV expressing Human PCDH8.

AAV-218331

AAV-h-PCDH8

Ready-to-use AAV expressing Human PCDH8 (protocadherin 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARCADLIN; PAPC

Description (Vector)

PCDH8 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Gene ID

5100

Gene Name (Vector)

protocadherin 8

Gene Symbol

PCDH8

HGNC ID

HGNC:8660

ORF Size (aa)

3213

ORF Size (bp)

3213 bp

RefSeq ID

NM_002590

RefSeq Synonyms

NM_032949, NM_002590, BC036025,

Species

human

UniGene ID

Hs.19492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.