human PCCB Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-218315
Availability:
3-5 weeks
Name:
AAV-h-PCCB
This is an AAV expressing Human PCCB.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PCCB
- Gene Name
- propionyl-CoA carboxylase beta subunit
- Gene ID
- 5096
- ORF Size
- 1620 bp
- RefSeq#
- BC013768
- Gene Description
- PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.63788
- HGNC ID
- HGNC:8654
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