human RNF5 Over-expression AAV

Name 
AAV-h-RNF5
Cat No 
AAV-218292
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RNF5.

AAV-218292
AAV-h-RNF5

Ready-to-use AAV expressing Human RNF5 (ring finger protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase RNF5; HsRma1; protein G16; ram1 homolog; RING finger protein 5; ring finger protein 5, E3 ubiquitin protein ligase; RING5; RING-type E3 ubiquitin transferase RNF5; RMA1
Description (eCommerce)
RNF5 (ring finger protein 5) is a membrane-bound E3 ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions [taken from NCBI Entrez Gene (Gene ID: 6048)].
Description (Vector)
RNF5 contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
Gene ID
6048
Gene Name (eCommerce)
ring finger protein 5
Gene Name (Vector)
ring finger protein 5
Gene Symbol
RNF5
HGNC ID
HGNC:10068
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
543
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RNF5
RefSeq ID
NM_006913
RefSeq Synonyms
NM_006913, BC148255, BC127652, BC127651, BC119742, BC119741, BC111392, BC004155,
Research Areas
Mitochondrion,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RNF5 (ring finger protein 5) is a membrane-bound E3 ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions [taken from NCBI Entrez Gene (Gene ID: 6048)].
UniGene ID
Hs.718462
UniProt ID (eCommerce)
Q99942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.