human PAX3 Over-expression AAV

Name 
AAV-h-PAX3
Cat No 
AAV-218272
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PAX3.

AAV-218272
AAV-h-PAX3

Ready-to-use AAV expressing Human PAX3 (paired box 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDHS; HUP2; WS1; WS3
Description (Vector)
PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Gene ID
5077
Gene Name (Vector)
paired box 3
Gene Symbol
PAX3
HGNC ID
HGNC:8617
ORF Size (aa)
1455
ORF Size (bp)
1455 bp
RefSeq ID
NM_000438
RefSeq Synonyms
NM_181461, NM_181460, NM_181459, NM_181458, NM_181457, NM_013942, NM_001127366, NM_000438, BC114363, BC101302, BC101301, BC101300, BC101299,
Species
human
UniGene ID
Hs.42146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.