human PAPD5 Over-expression AAV

Name 
AAV-h-PAPD5
Cat No 
AAV-218189
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PAPD5.

AAV-218189
AAV-h-PAPD5

Ready-to-use AAV expressing Human PAPD5 (poly(A) RNA polymerase D5, non-canonical). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; PAPD5; poly(A) RNA polymerase D5, non-canonical; Terminal nucleotidyltransferase 4B; terminal uridylyltransferase 3; topoisomerase-related function protein 4-2; TRF4-2; TUT3; TUTase 3
Description (eCommerce)
Non-canonical poly(A) RNA polymerase PAPD5, also called terminal uridylyltransferase 3 (TUTase 3), is encoded for by the gene PAPD5. TUTase 3 is the catalytic subunit of a TRAMP-like complex which has poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. PAPD5 plays a role in replication-dependent histone mRNA degradation and may play a role in sister chromatid cohesion [taken from UniProtKB (Entry: Q8NDF8)].
Gene ID
64282
Gene Name (eCommerce)
terminal nucleotidyltransferase 4B
Gene Name (Vector)
poly(A) RNA polymerase D5, non-canonical
Gene Symbol
PAPD5
HGNC ID
HGNC:30758
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
Protein Name (eCommerce)
Non-canonical poly(A) RNA polymerase PAPD5
RefSeq ID
NM_001040285
RefSeq Synonyms
NM_001040285, NM_001040284, BC157079, BC156329,
Research Areas
Cell Biology,Cell Cycle,Cell Division,DNA Replication,mRNA Processing,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Non-canonical poly(A) RNA polymerase PAPD5, also called terminal uridylyltransferase 3 (TUTase 3), is encoded for by the gene PAPD5. TUTase 3 is the catalytic subunit of a TRAMP-like complex which has poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. PAPD5 plays a role in replication-dependent histone mRNA degradation and may play a role in sister chromatid cohesion [taken from UniProtKB (Entry: Q8NDF8)].
UniGene ID
Hs.514342
UniProt ID (eCommerce)
Q8NDF8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.