human OSCAR Over-expression AAV

Name 
AAV-h-OSCAR
Cat No 
AAV-217958
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human OSCAR.

AAV-217958
AAV-h-OSCAR

Ready-to-use AAV expressing Human OSCAR (osteoclast associated, immunoglobulin-like receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PIgR-3; PIGR3
Description (Vector)
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
126014
Gene Name (Vector)
osteoclast associated, immunoglobulin-like receptor
Gene Symbol
OSCAR
HGNC ID
HGNC:29960
ORF Size (aa)
849
RefSeq ID
NM_130771
RefSeq Synonyms
NM_206818, NM_133169, NM_133168, NM_130771, NM_001282350, NM_001282349, BC035023,
Species
human
UniGene ID
Hs.347655

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.